Am I writing about actual science? Yes, apparently so. Thing is, the American Physiological Society has graciously decided that all corresponding authors of reviews and editorials would get 50 free reprints (useless), or a toll-free link (useful). However, in order to use said link you have to provide a specific URL of origin, wherein lies the problem. I don't trust the university to maintain my homepage anymore seeing as they just closed it down in favour of their new database-based system that I cannot do stuff with. So, this is the post where I will place the link.
The article was an invited review connected to an abstract sent to Experimental Biology 2014 in San Diego. It is basically a walk-through of how nervous and hormonal signalling affects kidney function in heart failure and thus contribute to the development of edema, and the worsening of both heart failure and kidney function in a vicious circle.
The title is: Renal neurohormonal regulation in heart failure decompensation, and it was written together with my present students Sofia, Mediha, and Jacqueline who are still in the lab, and Fredrik who have since moved on to his clinical internship.
For the time being you will have to make do with a (non-toll free) link to the article: LINK
Edit: Here is the toll-free link: Renal neurohormonal regulation in heart failure decompensation. By Sofia Jönsson (PhD-student), Mediha Becirovic Agic (PhD-student), Fredrik Narfström (MD-student), Jacqueline Melville (postdoc), and me.
Showing posts with label Experimental Biology. Show all posts
Showing posts with label Experimental Biology. Show all posts
Wednesday, July 23, 2014
Sunday, April 15, 2012
Conference-season 2012
For conference-season this year I have two major meetings planned. I have done my share of extra time in the A&E during Easter to be able to go without using up my vacation. First, I am bringing two students to Experimental Biology in San Diego. Then, I am going to London for the 22nd annual meeting of the European Society of Hypertension where I have to present my data myself.
This year both societies are providing iPhone apps with the program: EB2012 and iESH2012. The Experimental Biology is actually available for Android as well. The EB-App works brilliantly, while the ESH-App shows nothing what so ever at the moment. The screen-captures in the app-store looks promising, so I understand it as if the App will be some kind of live-update thingy. That does not really help me now when I try to plan ahead.
Using the brilliant round-trip planner kayak.se I even managed to book a round-trip flight so that I do not have to go back to Sweden in-between or something equally stupid.
Having spent all my time in the A&E and helping put together the posters for EB, I am hopelessly behind in constructing my own poster. If I had had a talk it would have been much simpler. Then I could have kept preparing and changing it until the last minute, or at least the day before. Now I have to have time to print it before-hand.
So, maybe I should not sit here blogging. I will, however, try to report something from the meetings once I am there.
This year both societies are providing iPhone apps with the program: EB2012 and iESH2012. The Experimental Biology is actually available for Android as well. The EB-App works brilliantly, while the ESH-App shows nothing what so ever at the moment. The screen-captures in the app-store looks promising, so I understand it as if the App will be some kind of live-update thingy. That does not really help me now when I try to plan ahead.
Using the brilliant round-trip planner kayak.se I even managed to book a round-trip flight so that I do not have to go back to Sweden in-between or something equally stupid.
Having spent all my time in the A&E and helping put together the posters for EB, I am hopelessly behind in constructing my own poster. If I had had a talk it would have been much simpler. Then I could have kept preparing and changing it until the last minute, or at least the day before. Now I have to have time to print it before-hand.
So, maybe I should not sit here blogging. I will, however, try to report something from the meetings once I am there.
Monday, April 26, 2010
Experimental Biology - poster day
With a cold.
Anyway, yesterday did serve some quite nice talks and a couple of nice posters, but I was having the sniffles, so I don't remember shit. I did stay the course and at five I went the the hotel to rest a little before going out for dinner. I woke up at four in the morning again, couldn't go back to sleep (understandably), so here I am.
I have my posters today. The poster sessions are often one of the best parts of meetings like Experimental Biology - You get to chat for a bit longer with people who are actually interested in what you have done.
Today I am going to stay awake so that I can go out for some beer and dinner. Now I am really hungry - having not eaten since lunch yesterday - I am going to breakfast.
Anyway, yesterday did serve some quite nice talks and a couple of nice posters, but I was having the sniffles, so I don't remember shit. I did stay the course and at five I went the the hotel to rest a little before going out for dinner. I woke up at four in the morning again, couldn't go back to sleep (understandably), so here I am.
I have my posters today. The poster sessions are often one of the best parts of meetings like Experimental Biology - You get to chat for a bit longer with people who are actually interested in what you have done.
Today I am going to stay awake so that I can go out for some beer and dinner. Now I am really hungry - having not eaten since lunch yesterday - I am going to breakfast.
Sunday, April 25, 2010
Experimental Biology - first morning
It is conference time for physiologists. Experimental Biology is by far the largest meeting for physiologists, and this year it's in Anaheim, California, right beside Disney Land. Now it's the morning of the second day. It is 5.30am and I can't sleep.
It started yesterday with the traditional refresher course. I feel a little bad for them, because I just couldn't take four hours of sitting down, so I only stayed for the first two and a half - even though the last talk looked like lots of fun. Of course, now in the days of the internet, I can just go and listen to the recording at www.the-aps.org/education/refresher.
The first two were really good, Donna Korzick talked about how:
"The Heart Develops Pressure, And Pressure Makes the Blood 'Go Round"
Which turned out to be mostly charge excitation coupling and pacemaker activity, including some exciting new data on how local calcium releases actually drives the slow depolarisation (see Lakatta et al, Circ Res, 106: 659-673, 2010).
Then Philip Clifford talked about "Local control of blood flow." He showed some really nifty confocal images of vascular structure and then talked about autoregulation. Not proper, renal autoregulation, but the sloppy kind you find in other organs. Most interestingly he pointed out that the myogenic response is a quite slow mechanism in muscle tissue, for example. Taking somewhere around two minutes to return blood flow to normal after a perturbation. In the kidney, bloodflow quickly stabilizes (20-30 seconds) following a perturbation. Although some of this is probably because of interactions between the myogenic response and the tubuloglomerular feedback, I think I brought home that myogenic response is faster in the kidney.
The afternoon brought a guest appearance of renal circulatory physiology at the micro circulatory society. You might call it a refresher course in renal autoregulation and afferent arteriolar function provided by the usual suspects, Arendshorst, Peti-Peterdi, Inscho. There was a small detour to the medulla. Pallone presented some very interesting data on how water shunting from the descending vasa recta to the ascending helps increase the concentrating capacity.
Last of the days lectures was the Walter B. Cannon memorial award lecture. This year it was awarded to JJ. Fredberd of the Harvard School of Public Health, an engineer who works in pulmonary physiology and probably wil receive the Nobel Prize in medicine for his evolutionary findings. A fantastic lecture, where he presented more novel ideas (with supporting data) in less time than anyone I have met in recent memory. In short, cells are soft as shaving foam because it makes them capable of eating their neighbours and/or crawling around. This explains the development of the eucaryote. I will have to study this for years before I understand it, maybe I will attempt a post on the implications for renal physiology at some later time.
Finally it was time for the free food and free beer, i.e. the opening reception.
The time when the breakfast buffet opens is approaching and I have to go.
/M
It started yesterday with the traditional refresher course. I feel a little bad for them, because I just couldn't take four hours of sitting down, so I only stayed for the first two and a half - even though the last talk looked like lots of fun. Of course, now in the days of the internet, I can just go and listen to the recording at www.the-aps.org/education/refresher.
The first two were really good, Donna Korzick talked about how:
"The Heart Develops Pressure, And Pressure Makes the Blood 'Go Round"
Which turned out to be mostly charge excitation coupling and pacemaker activity, including some exciting new data on how local calcium releases actually drives the slow depolarisation (see Lakatta et al, Circ Res, 106: 659-673, 2010).
Then Philip Clifford talked about "Local control of blood flow." He showed some really nifty confocal images of vascular structure and then talked about autoregulation. Not proper, renal autoregulation, but the sloppy kind you find in other organs. Most interestingly he pointed out that the myogenic response is a quite slow mechanism in muscle tissue, for example. Taking somewhere around two minutes to return blood flow to normal after a perturbation. In the kidney, bloodflow quickly stabilizes (20-30 seconds) following a perturbation. Although some of this is probably because of interactions between the myogenic response and the tubuloglomerular feedback, I think I brought home that myogenic response is faster in the kidney.
The afternoon brought a guest appearance of renal circulatory physiology at the micro circulatory society. You might call it a refresher course in renal autoregulation and afferent arteriolar function provided by the usual suspects, Arendshorst, Peti-Peterdi, Inscho. There was a small detour to the medulla. Pallone presented some very interesting data on how water shunting from the descending vasa recta to the ascending helps increase the concentrating capacity.
Last of the days lectures was the Walter B. Cannon memorial award lecture. This year it was awarded to JJ. Fredberd of the Harvard School of Public Health, an engineer who works in pulmonary physiology and probably wil receive the Nobel Prize in medicine for his evolutionary findings. A fantastic lecture, where he presented more novel ideas (with supporting data) in less time than anyone I have met in recent memory. In short, cells are soft as shaving foam because it makes them capable of eating their neighbours and/or crawling around. This explains the development of the eucaryote. I will have to study this for years before I understand it, maybe I will attempt a post on the implications for renal physiology at some later time.
Finally it was time for the free food and free beer, i.e. the opening reception.
The time when the breakfast buffet opens is approaching and I have to go.
/M
Friday, January 01, 2010
Supporting undergraduate research
Go over to Isis the goddess's blog. She's donating January's proceeds to an undergraduate award to be presented at Experimental Biology in Anaheim. Fantastic initiative, especially when you have traffic enough to provide for an extra awardee of the David Bruce Award, as Isis does.
In her honour I'm posting a shoe today. It's my favourite shoe. I wear it almost all the time. Every day at work, and every summer from April through September. Its simple design and stylish looks makes it the perfect shoe for daily casual wear as well as for jacket and tie occasions.
I present the Birkenstock!
Birkenstock sandals, new and one that's a year old. I don't know what it is but they wear out fast when I use them.
Yours,
Michael
In her honour I'm posting a shoe today. It's my favourite shoe. I wear it almost all the time. Every day at work, and every summer from April through September. Its simple design and stylish looks makes it the perfect shoe for daily casual wear as well as for jacket and tie occasions.
I present the Birkenstock!
Birkenstock sandals, new and one that's a year old. I don't know what it is but they wear out fast when I use them.
Yours,
Michael
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